human UNC45A shRNA silencing AAV

Name 
AAV-h-UNC45A-shRNA
Cat No 
shAAV-227188
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human UNC45A.

shAAV-227188
AAV-h-UNC45A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UNC45A (unc-45 myosin chaperone A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GC-UNC45; GCUNC-45; GCUNC45; IRO039700; SMAP-1; SMAP1; UNC-45A
Description (Vector)
UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 (PubMed 12356907); Chadli et al., 2006 (PubMed 16478993)).(supplied by OMIM, Mar 2008)
Gene ID
55898
Gene Name (Vector)
unc-45 myosin chaperone A
Gene Symbol
UNC45A
HGNC ID
HGNC:30594
ORF Size (aa)
2790
ORF Size (bp)
2790 bp
RefSeq ID
NM_018671
RefSeq Synonyms
NM_018671, NM_001323621, NM_001323620, NM_001323619, NM_001039675, BC045635, BC037992, BC006214,
Species
human
UniGene ID
Hs.389461

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.