human UGP2 shRNA silencing AAV

Name
AAV-h-UGP2-shRNA

Cat No
shAAV-227138

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human UGP2.

shAAV-227138

AAV-h-UGP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UGP2 (UDP-glucose pyrophosphorylase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

pHC379; UDPG; UDPGP; UDPGP2; UGP1; UGPP1; UGPP2

Description (Vector)

The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

7360

Gene Name (Vector)

UDP-glucose pyrophosphorylase 2

Gene Symbol

UGP2

HGNC ID

HGNC:12527

ORF Size (aa)

1494

ORF Size (bp)

1494 bp

RefSeq ID

NM_006759

RefSeq Synonyms

NM_006759, NM_001001521, BC047004, BC002954, BC000173,

Species

human

UniGene ID

Hs.516217

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.