human UCK2 shRNA silencing AAV

Name 
AAV-h-UCK2-shRNA
Cat No 
shAAV-227107
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human UCK2.

shAAV-227107
AAV-h-UCK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UCK2 (uridine-cytidine kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cytidine monophosphokinase 2; testis-specific protein TSA903; TSA903; UCK 2; UK; UMPK; uridine kinase; uridine monophosphate kinase; uridine monophosphokinase 2; uridine-cytidine kinase 2
Description (eCommerce)
Uridine monophosphokinase 2 (UCK2) is a pyrimidine ribonucleoside kinase. UCK2 catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectivel [taken from NCBI Entrez Gene (Gene ID: 7371)].
Description (Vector)
UCK2 encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively.
Gene ID
7371
Gene Name (eCommerce)
uridine-cytidine kinase 2
Gene Name (Vector)
uridine-cytidine kinase 2
Gene Symbol
UCK2
HGNC ID
HGNC:12562
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
786
Protein Name (eCommerce)
Uridine-cytidine kinase 2
RefSeq ID
NM_012474
RefSeq Synonyms
NM_012474, BC002906,
Research Areas
Metabolism/Metabolic Process,Neurobiology
Research Areas (Faceted)
cell_biology,metabolism,neurobiology
Species
human
Target Sentence
Uridine monophosphokinase 2 (UCK2) is a pyrimidine ribonucleoside kinase. UCK2 catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectivel [taken from NCBI Entrez Gene (Gene ID: 7371)].
UniGene ID
Hs.458360
UniProt ID (eCommerce)
Q9BZX2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.