human TYW3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TYW3.
shAAV-226948
AAV-h-TYW3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TYW3 (tRNA-yW synthesizing protein 3 homolog). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C1orf171
Description (Vector)
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).(supplied by OMIM, Mar 2008)
Gene ID
127253
Gene Name (Vector)
tRNA-yW synthesizing protein 3 homolog
Gene Symbol
TYW3
HGNC ID
HGNC:24757
ORF Size (aa)
780
RefSeq ID
NM_138467
RefSeq Synonyms
NM_138467, NM_001162916, BC071765,
Species
human
UniGene ID
Hs.348411
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.