human TUB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TUB.
shAAV-226767
AAV-h-TUB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TUB (tubby bipartite transcription factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
rd5; RDOB
Description (Vector)
TUB encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
7275
Gene Name (Vector)
tubby bipartite transcription factor
Gene Symbol
TUB
HGNC ID
HGNC:12406
ORF Size (aa)
1686
ORF Size (bp)
1686 bp
RefSeq ID
NM_177972
RefSeq Synonyms
NM_177972, NM_003320, BC075032, BC075031,
Species
human
UniGene ID
Hs.568986
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.