human TTC37 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TTC37.
shAAV-226712
AAV-h-TTC37-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TTC37 (tetratricopeptide repeat domain 37). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
KIAA0372; Ski3; SKI3 homolog; tetratricopeptide repeat protein 37; THES; thespin; TPR repeat protein 37; tricho-hepatic-enteric syndrome protein
Description (eCommerce)
TTC37 is a component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6PGP7].
Description (Vector)
TTC37 encodes a protein with twenty tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Mutations in this gene are associated with trichohepatoenteric syndrome.
Gene ID
9652
Gene Name (eCommerce)
tetratricopeptide repeat domain 37
Gene Name (Vector)
tetratricopeptide repeat domain 37
Gene Symbol
TTC37
HGNC ID
HGNC:23639
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4695
ORF Size (bp)
4695 bp
Protein Name (eCommerce)
Tetratricopeptide repeat protein 37
RefSeq ID
NM_014639
RefSeq Synonyms
NM_014639, BC056893,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
TTC37 is a component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C). [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6PGP7].
UniGene ID
Hs.482868
UniProt ID (eCommerce)
Q6PGP7
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.