human DSE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DSE.
shAAV-226658
AAV-h-DSE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DSE (dermatan sulfate epimerase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DS-epi1; DSEP; DSEPI; EDSMC2; SART-2; SART2
Description (Vector)
DSE is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
29940
Gene Name (Vector)
dermatan sulfate epimerase
Gene Symbol
DSE
HGNC ID
HGNC:21144
ORF Size (aa)
2877
ORF Size (bp)
2877 bp
RefSeq ID
NM_013352
RefSeq Synonyms
NM_013352, NM_001322944, NM_001322943, NM_001322941, NM_001322940, NM_001322939, NM_001322938, NM_001322937, NM_001080976, BC039245,
Species
human
UniGene ID
Hs.486292
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.