human TRPC5 shRNA silencing AAV

Name
AAV-h-TRPC5-shRNA

Cat No
shAAV-226544

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TRPC5.

shAAV-226544

AAV-h-TRPC5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRPC5 (transient receptor potential cation channel subfamily C member 5). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PPP1R159; TRP5

Description (Vector)

TRPC5 belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1).

Gene ID

7224

Gene Name (Vector)

transient receptor potential cation channel subfamily C member 5

Gene Symbol

TRPC5

HGNC ID

HGNC:12337

ORF Size (aa)

2922

ORF Size (bp)

2922 bp

RefSeq ID

NM_012471

RefSeq Synonyms

NM_012471, BC137274, BC137271,

Species

human

UniGene ID

Hs.657709

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.