human TRMT6 shRNA silencing AAV

Name 
AAV-h-TRMT6-shRNA
Cat No 
shAAV-226522
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TRMT6.

shAAV-226522
AAV-h-TRMT6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRMT6 (tRNA methyltransferase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CGI-09; GCD10; Gcd10p; mRNA methyladenosine-N(1)-methyltransferase non-catalytic subunit TRM6; tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; tRNA methyltransferase 6 homolog; tRNA(m1A58)-methyltransferase subunit TRM6; tRNA(m1A58)MTase subunit TRM6
Description (eCommerce)
tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 is a substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9UJA5].
Description (Vector)
TRMT6 is similar to an uncharacterized protein from C. elegans. Although the function of the encoded protein is unknown, it shares weak sequence similarity to a region of S. cerevisiae translation initiation factor subunit Gcd10p.
Gene ID
51605
Gene Name (eCommerce)
tRNA methyltransferase 6
Gene Name (Vector)
tRNA methyltransferase 6
Gene Symbol
TRMT6
HGNC ID
HGNC:20900
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1494
ORF Size (bp)
1494 bp
Protein Name (eCommerce)
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6
RefSeq ID
NM_015939
RefSeq Synonyms
NM_015939, NM_001281467, BC001262,
Research Areas
Neurobiology,RNA Processing,Translational Control
Research Areas (Faceted)
cell_biology,genetics,neurobiology,transcription_translation
Species
human
Target Sentence
tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 is a substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9UJA5].
UniGene ID
Hs.128791
UniProt ID (eCommerce)
Q9UJA5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.