human TRIP10 shRNA silencing AAV

Name 
AAV-h-TRIP10-shRNA
Cat No 
shAAV-226495
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TRIP10.

shAAV-226495
AAV-h-TRIP10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRIP10 (thyroid hormone receptor interactor 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cdc42-interacting protein 4; CIP4; HSTP; protein Felic; salt tolerant protein; salt tolerator; STOT; STP; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10
Description (eCommerce)
TRIP10/CIP4 is a multi-functional adapter protein and plays a role in the translocation of Glut4 (glucose transporter) vesicles to the cell surface in response to insulin. TRIP10/CIP4 has also been found to interact with the active GTPases CDC42 and TC10 as well as the Wiskott-Aldrich syndrome protein (WASP), a protein involved in cytoskeletal organization. Recent studies suggest that CIP4 accumulation may play a role in Huntington’s disease pathogenesis.
Gene ID
9322
Gene Name (eCommerce)
thyroid hormone receptor interactor 10
Gene Name (Vector)
thyroid hormone receptor interactor 10
Gene Symbol
TRIP10
HGNC ID
HGNC:12304
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1638
ORF Size (bp)
1638 bp
Protein Name (eCommerce)
Cdc42-interacting protein 4
RefSeq ID
NM_004240
RefSeq Synonyms
NM_004240, NM_001288963, NM_001288962, BC013002,
Research Areas
Cytoskeleton,Golgi Apparatus,Insulin Signaling,Lysosome,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
TRIP10/CIP4 is a multi-functional adapter protein and plays a role in the translocation of Glut4 (glucose transporter) vesicles to the cell surface in response to insulin. TRIP10/CIP4 has also been found to interact with the active GTPases CDC42 and TC10 as well as the Wiskott-Aldrich syndrome protein (WASP), a protein involved in cytoskeletal organization. Recent studies suggest that CIP4 accumulation may play a role in Huntington’s disease pathogenesis.
UniGene ID
Hs.515094
UniProt ID (eCommerce)
Q15642

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.