human TRIM6 shRNA silencing AAV

Name
AAV-h-TRIM6-shRNA

Cat No
shAAV-226462

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TRIM6.

shAAV-226462

AAV-h-TRIM6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TRIM6 (tripartite motif containing 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RNF89

Description (Vector)

TRIM6 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members.

Gene ID

117854

Gene Name (Vector)

tripartite motif containing 6

Gene Symbol

TRIM6

HGNC ID

HGNC:16277

ORF Size (aa)

1188

RefSeq ID

NM_058166

RefSeq Synonyms

NM_058166, NM_001198645, NM_001198644, NM_001003818, BC065575, BC047564,

Species

human

UniGene ID

Hs.125300

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.