human TRDMT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TRDMT1.
shAAV-226362
AAV-h-TRDMT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TRDMT1 (tRNA aspartic acid methyltransferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DMNT2; DNMT2; MHSAIIP; PUMET; RNMT1
Description (Vector)
TRDMT1 encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.
Gene ID
1787
Gene Name (Vector)
tRNA aspartic acid methyltransferase 1
Gene Symbol
TRDMT1
HGNC ID
HGNC:2977
ORF Size (aa)
1176
RefSeq ID
NM_004412
RefSeq Synonyms
NM_004412, NM_001321007, NM_001321006, BC047733,
Species
human
UniGene ID
Hs.351665
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.