human TOP3A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TOP3A.
shAAV-226206
AAV-h-TOP3A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TOP3A (topoisomerase (DNA) III alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TOP3; ZGRF7
Description (Vector)
TOP3A encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells.
Gene ID
7156
Gene Name (Vector)
topoisomerase (DNA) III alpha
Gene Symbol
TOP3A
HGNC ID
HGNC:11992
ORF Size (aa)
3006
ORF Size (bp)
3006 bp
RefSeq ID
NM_004618
RefSeq Synonyms
NM_004618, NM_001320759, BC051748,
Species
human
UniGene ID
Hs.592115
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.