human TOE1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TOE1.
shAAV-226173
AAV-h-TOE1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TOE1 (target of EGR1, member 1 (nuclear)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hCaf1; ZPCH7; target of EGR1 protein 1; target of EGR1, member 1 (nuclear)
Description (eCommerce)
Target of EGR1 protein 1 (TOE1) inhibits cell growth rate and cell cycle. It induces CDKN1A expression as well as TGF-beta expression. TOE1 also mediates the inhibitory growth effect of EGR1 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96GM8].
Gene ID
114034
Gene Name (eCommerce)
target of EGR1, exonuclease
Gene Name (Vector)
target of EGR1, member 1 (nuclear)
Gene Symbol
TOE1
HGNC ID
HGNC:15954
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1533
ORF Size (bp)
1533 bp
Protein Name (eCommerce)
Target of EGR1 protein 1
RefSeq ID
NM_025077
RefSeq Synonyms
NM_025077, BC009364,
Research Areas
Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Target of EGR1 protein 1 (TOE1) inhibits cell growth rate and cell cycle. It induces CDKN1A expression as well as TGF-beta expression. TOE1 also mediates the inhibitory growth effect of EGR1 [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96GM8].
UniGene ID
Hs.525091
UniProt ID (eCommerce)
Q96GM8
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.