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human TNRC6C shRNA silencing AAV

Name 
AAV-h-TNRC6C-shRNA
Cat No 
shAAV-226160
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TNRC6C.

shAAV-226160
AAV-h-TNRC6C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TNRC6C (trinucleotide repeat containing 6C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
trinucleotide repeat-containing gene 6C protein
Description (eCommerce)
Trinucleotide repeat-containing gene 6C protein (TNRC6C) plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). TNRC6C is required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9HCJ0].
Gene ID
57690
Gene Name (eCommerce)
trinucleotide repeat containing 6C
Gene Name (Vector)
trinucleotide repeat containing 6C
Gene Symbol
TNRC6C
HGNC ID
HGNC:29318
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5070
ORF Size (bp)
5070 bp
Protein Name (eCommerce)
Trinucleotide repeat-containing gene 6C protein
RefSeq ID
NM_018996
RefSeq Synonyms
NM_018996, NM_001142640, BC157115, BC156366,
Research Areas
B-cell Receptor Signaling,Cancer,EGFR Signaling,EGFR Signaling in Cancer,Fc Receptor Signaling,FGF Signaling,Gene Expression,Immunology,Innate Immunity,Neurobiology,NGF Signaling,Notch Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,RNA Binding,SCF-KIT Signaling,Signal Transduction,Translational Control
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,immunology,neurobiology,signal_transduction,stem_cell_biology,transcription_translation
Species
human
Target Sentence
Trinucleotide repeat-containing gene 6C protein (TNRC6C) plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). TNRC6C is required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9HCJ0].
UniGene ID
Hs.584945
UniProt ID (eCommerce)
Q9HCJ0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.