human TNPO3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TNPO3.
shAAV-226152
AAV-h-TNPO3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TNPO3 (transportin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IPO12; LGMD1F; MTR10A; TRN-SR; TRN-SR2; TRNSR
Description (Vector)
TNPO3 is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.
Gene ID
23534
Gene Name (Vector)
transportin 3
Gene Symbol
TNPO3
HGNC ID
HGNC:17103
ORF Size (aa)
2772
ORF Size (bp)
2772 bp
RefSeq ID
NM_012470
RefSeq Synonyms
NM_012470, NM_001191028, BC172512, BC156517,
Species
human
UniGene ID
Hs.193613
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.