human TNNT2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TNNT2.
shAAV-226142
AAV-h-TNNT2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TNNT2 (troponin T2, cardiac type). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TnTC
Description (Vector)
TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Gene ID
7139
Gene Name (Vector)
troponin T2, cardiac type
Gene Symbol
TNNT2
HGNC ID
HGNC:11949
ORF Size (aa)
858
RefSeq ID
NM_000364
RefSeq Synonyms
NM_001276347, NM_001276346, NM_001276345, NM_001001432, NM_001001431, NM_001001430, NM_000364, BC002653,
Species
human
UniGene ID
Hs.533613
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.