human TNFSF14 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TNFSF14.
shAAV-226103
AAV-h-TNFSF14-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TNFSF14 (tumor necrosis factor superfamily member 14). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD258; HVEML; LIGHT; LTg
Description (Vector)
TNFSF14 is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
Gene ID
8740
Gene Name (Vector)
tumor necrosis factor superfamily member 14
Gene Symbol
TNFSF14
HGNC ID
HGNC:11930
ORF Size (aa)
720
RefSeq ID
NM_003807
RefSeq Synonyms
NM_172014, NM_003807, BC152848, BC018058,
Species
human
UniGene ID
Hs.129708
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.