human TNFSF13 shRNA silencing AAV

Name
AAV-h-TNFSF13-shRNA

Cat No
shAAV-226101

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TNFSF13.

shAAV-226101

AAV-h-TNFSF13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TNFSF13 (tumor necrosis factor superfamily member 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

APRIL; CD256; TALL-2; TALL2; TNLG7B; TRDL-1; UNQ383/PRO715; ZTNF2

Description (Vector)

TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

Gene ID

8741

Gene Name (Vector)

tumor necrosis factor superfamily member 13

Gene Symbol

TNFSF13

HGNC ID

HGNC:11928

ORF Size (aa)

744

RefSeq ID

NM_003808

RefSeq Synonyms

NM_172088, NM_172087, NM_003808, NM_001198624, NM_001198623, NM_001198622, BC008042,

Species

human

UniGene ID

Hs.54673

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.