human TNFRSF10A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TNFRSF10A.
shAAV-226068
AAV-h-TNFRSF10A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TNFRSF10A (TNF receptor superfamily member 10a). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APO2; CD261; DR4; TRAILR-1; TRAILR1
Description (Vector)
TNFRSF10A is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
Gene ID
8797
Gene Name (Vector)
TNF receptor superfamily member 10a
Gene Symbol
TNFRSF10A
HGNC ID
HGNC:11904
ORF Size (aa)
1407
ORF Size (bp)
1407 bp
RefSeq ID
NM_003844
RefSeq Synonyms
NM_003844, BC012866,
Species
human
UniGene ID
Hs.591834
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.