human TMTC3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TMTC3.
shAAV-226041
AAV-h-TMTC3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TMTC3 (transmembrane and tetratricopeptide repeat containing 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LIS8; Protein SMILE; SMILE; transmembrane and TPR repeat-containing protein 3
Description (eCommerce)
Transmembrane and TPR repeat-containing protein 3 (TMTC3) is involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress respons [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6ZXV5].
Description (Vector)
TMTC3 encodes a protein that belongs to the transmembrane and tetratricopeptide repeat-containing protein family.
Gene ID
160418
Gene Name (eCommerce)
transmembrane and tetratricopeptide repeat containing 3
Gene Name (Vector)
transmembrane and tetratricopeptide repeat containing 3
Gene Symbol
TMTC3
HGNC ID
HGNC:26899
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2745
ORF Size (bp)
2745 bp
Protein Name (eCommerce)
Transmembrane and TPR repeat-containing protein 3
RefSeq ID
NM_181783
RefSeq Synonyms
NM_181783, BC117177, BC117175,
Research Areas
Cell Biology,Translational Control,Transport
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Transmembrane and TPR repeat-containing protein 3 (TMTC3) is involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress respons [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6ZXV5].
UniGene ID
Hs.331268
UniProt ID (eCommerce)
Q6ZXV5
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.