human TMPRSS11D shRNA silencing AAV

Name 
AAV-h-TMPRSS11D-shRNA
Cat No 
shAAV-226006
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TMPRSS11D.

shAAV-226006
AAV-h-TMPRSS11D-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TMPRSS11D (transmembrane protease, serine 11D). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HAT
Description (Vector)
TMPRSS11D encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
Gene ID
9407
Gene Name (Vector)
transmembrane protease, serine 11D
Gene Symbol
TMPRSS11D
HGNC ID
HGNC:24059
ORF Size (aa)
1257
ORF Size (bp)
1257 bp
RefSeq ID
NM_004262
RefSeq Synonyms
NM_004262, BC125196, BC125195,
Species
human
UniGene ID
Hs.132195

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.