human GLB1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GLB1.
shAAV-226003
AAV-h-GLB1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GLB1 (galactosidase beta 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EBP; ELNR1; MPS4B
Description (Vector)
GLB1 encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
2720
Gene Name (Vector)
galactosidase beta 1
Gene Symbol
GLB1
HGNC ID
HGNC:4298
ORF Size (aa)
2034
ORF Size (bp)
2034 bp
RefSeq ID
NM_000404
RefSeq Synonyms
NM_001317040, NM_001135602, NM_001079811, NM_000404, BC007493,
Species
human
UniGene ID
Hs.443031
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.