human TMIE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TMIE.
shAAV-225991
AAV-h-TMIE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TMIE (transmembrane inner ear). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DFNB6
Description (Vector)
TMIE encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. TMIE is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment.
Gene ID
259236
Gene Name (Vector)
transmembrane inner ear
Gene Symbol
TMIE
HGNC ID
HGNC:30800
ORF Size (aa)
468
RefSeq ID
NM_147196
RefSeq Synonyms
NM_147196, BC126260, BC126258,
Species
human
UniGene ID
Hs.185777
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.