human TMEM70 shRNA silencing AAV

Name 
AAV-h-TMEM70-shRNA
Cat No 
shAAV-225952
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TMEM70.

shAAV-225952
AAV-h-TMEM70-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TMEM70 (transmembrane protein 70). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MC5DN2
Description (Vector)
TMEM70 likely encodes a mitochondrial membrane protein. The encoded protein may play a role in biogenesis of mitochondrial ATP synthase. Mutations in this gene have been associated with neonatal mitochondrial encephalocardiomyopathy due to ATP synthase deficiency. Alternatively spliced transcript variants have been described.
Gene ID
54968
Gene Name (Vector)
transmembrane protein 70
Gene Symbol
TMEM70
HGNC ID
HGNC:26050
ORF Size (aa)
783
RefSeq ID
NM_017866
RefSeq Synonyms
NM_017866, NM_001040613, BC002748,
Species
human
UniGene ID
Hs.106650

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.