human TMEM214 shRNA silencing AAV

Name 
AAV-h-TMEM214-shRNA
Cat No 
shAAV-225859
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TMEM214.

shAAV-225859
AAV-h-TMEM214-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TMEM214 (transmembrane protein 214). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
transmembrane protein 214
Description (eCommerce)
TMEM214 is a critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6NUQ4].
Gene ID
54867
Gene Name (eCommerce)
transmembrane protein 214
Gene Name (Vector)
transmembrane protein 214
Gene Symbol
TMEM214
HGNC ID
HGNC:25983
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2070
ORF Size (bp)
2070 bp
Protein Name (eCommerce)
Transmembrane protein 214
RefSeq ID
NM_017727
RefSeq Synonyms
NM_017727, NM_001083590, BC068479,
Research Areas
Apoptosis
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
TMEM214 is a critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6NUQ4].
UniGene ID
Hs.533934
UniProt ID (eCommerce)
Q6NUQ4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.