human TMEM138 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TMEM138.
shAAV-225747
AAV-h-TMEM138-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TMEM138 (transmembrane protein 138). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HSPC196
Description (Vector)
TMEM138 encodes a multi-pass transmembrane protein. Reduced expression of this gene in mouse fibroblasts causes short cilia and failure of ciliogenesis. Expression of this gene is tightly coordinated with expression of the neighboring gene TMEM216. Mutations in this gene are associated with the autosomal recessive neurodevelopmental disorder Joubert Syndrome. Alternative splicing results in multiple transcript variants.
Gene ID
51524
Gene Name (Vector)
transmembrane protein 138
Gene Symbol
TMEM138
HGNC ID
HGNC:26944
ORF Size (aa)
489
RefSeq ID
NM_016464
RefSeq Synonyms
NM_016464, NM_001330281, BC005201,
Species
human
UniGene ID
Hs.406530
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.