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human TMC2 shRNA silencing AAV

Name 
AAV-h-TMC2-shRNA
Cat No 
shAAV-225648
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TMC2.

shAAV-225648
AAV-h-TMC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TMC2 (transmembrane channel like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C20orf145
Description (Vector)
TMC2 is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, expression in the inner ear suggests that it may be crucial for normal auditory function. Mutations in this gene may underlie hereditary disorders of balance and hearing.
Gene ID
117532
Gene Name (Vector)
transmembrane channel like 2
Gene Symbol
TMC2
HGNC ID
HGNC:16527
ORF Size (aa)
2670
ORF Size (bp)
2670 bp
RefSeq ID
NM_080751
RefSeq Synonyms
NM_080751, BC111450,
Species
human
UniGene ID
Hs.352626

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.