human TLR10 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TLR10.
shAAV-225584
AAV-h-TLR10-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TLR10 (toll like receptor 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD290
Description (Vector)
TLR10 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Gene ID
81793
Gene Name (Vector)
toll like receptor 10
Gene Symbol
TLR10
HGNC ID
HGNC:15634
ORF Size (aa)
2436
ORF Size (bp)
2436 bp
RefSeq ID
NM_030956
RefSeq Synonyms
NM_030956, NM_001195108, NM_001195107, NM_001195106, NM_001017388, BC109112, BC109111, BC089406,
Species
human
UniGene ID
Hs.120551
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.