human TINF2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TINF2.
shAAV-225537
AAV-h-TINF2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TINF2 (TERF1 interacting nuclear factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DKCA3; TIN2
Description (Vector)
TINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.
Gene ID
26277
Gene Name (Vector)
TERF1 interacting nuclear factor 2
Gene Symbol
TINF2
HGNC ID
HGNC:11824
ORF Size (aa)
1356
ORF Size (bp)
1356 bp
RefSeq ID
NM_012461
RefSeq Synonyms
NM_012461, NM_001099274, BC019343, BC005030,
Species
human
UniGene ID
Hs.496191
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.