human TIMP3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TIMP3.
shAAV-225533
AAV-h-TIMP3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TIMP3 (TIMP metallopeptidase inhibitor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HSMRK222; K222; K222TA2; SFD
Description (Vector)
TIMP3 belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
Gene ID
7078
Gene Name (Vector)
TIMP metallopeptidase inhibitor 3
Gene Symbol
TIMP3
HGNC ID
HGNC:11822
ORF Size (aa)
636
RefSeq ID
NM_000362
RefSeq Synonyms
NM_000362, BC014277,
Species
human
UniGene ID
Hs.644633
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.