human TIMM8B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TIMM8B.
shAAV-225525
AAV-h-TIMM8B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TIMM8B (translocase of inner mitochondrial membrane 8 homolog B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DDP2; TIM8B
Description (Vector)
TIMM8B encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. TIMM8B is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. TIMM8B is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.
Gene ID
26521
Gene Name (Vector)
translocase of inner mitochondrial membrane 8 homolog B
Gene Symbol
TIMM8B
HGNC ID
HGNC:11818
ORF Size (aa)
156
RefSeq ID
NM_012459
RefSeq Synonyms
NM_012459, BC106067, BC105986, BC000711,
Species
human
UniGene ID
Hs.279915
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.