human THOC5 shRNA silencing AAV

Name 
AAV-h-THOC5-shRNA
Cat No 
shAAV-225454
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human THOC5.

shAAV-225454
AAV-h-THOC5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human THOC5 (THO complex 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C22orf19; Fmip; Fms-interacting protein; fSAP79; functional spliceosome-associated protein 79; hTREX90; NF2/meningioma region protein pK1.3; PK1.3; placental protein 39.2; PP39.2; THO complex subunit 5 homolog
Description (eCommerce)
THOC5 is part of the splicesome complex. It has been identified as a target in macrophage-colony stimulating factor signaling and may have a potential role in leukemogenesis.
Gene ID
8563
Gene Name (eCommerce)
THO complex 5
Gene Name (Vector)
THO complex 5
Gene Symbol
THOC5
HGNC ID
HGNC:19074
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2052
ORF Size (bp)
2052 bp
Protein Name (eCommerce)
THO complex subunit 5 homolog
RefSeq ID
NM_003678
RefSeq Synonyms
NM_003678, NM_001002879, NM_001002878, NM_001002877, BC003615,
Research Areas
Cytoskeleton,Host-Virus Interactions,mRNA Processing,mRNA Splicing,mRNA transport,RNA Binding,RNA Processing,RNA Transport,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,infectious_disease,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
THOC5 is part of the splicesome complex. It has been identified as a target in macrophage-colony stimulating factor signaling and may have a potential role in leukemogenesis.
UniGene ID
Hs.75361
UniProt ID (eCommerce)
Q13769

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.