human TGFBR3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TGFBR3.
shAAV-225392
AAV-h-TGFBR3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TGFBR3 (transforming growth factor beta receptor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
betaglycan; BGCAN
Description (Vector)
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Gene ID
7049
Gene Name (Vector)
transforming growth factor beta receptor 3
Gene Symbol
TGFBR3
HGNC ID
HGNC:11774
ORF Size (aa)
2556
ORF Size (bp)
2556 bp
RefSeq ID
NM_003243
RefSeq Synonyms
NM_003243, NM_001195684, NM_001195683, BC136295, BC126116,
Species
human
UniGene ID
Hs.482390
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.