human TFF3 shRNA silencing AAV

Name
AAV-h-TFF3-shRNA

Cat No
shAAV-225362

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TFF3.

shAAV-225362

AAV-h-TFF3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TFF3 (trefoil factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ITF; P1B; TFI

Description (Vector)

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Gene ID

7033

Gene Name (Vector)

trefoil factor 3

Gene Symbol

TFF3

HGNC ID

HGNC:11757

ORF Size (aa)

222

RefSeq ID

NM_003226

RefSeq Synonyms

NM_003226, BC017859,

Species

human

UniGene ID

Hs.82961

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.