human TESK2 shRNA silencing AAV

Name
AAV-h-TESK2-shRNA

Cat No
shAAV-225318

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TESK2.

shAAV-225318

AAV-h-TESK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TESK2 (testis-specific kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

TESK2 product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. TESK2 is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis.

Gene ID

10420

Gene Name (Vector)

testis-specific kinase 2

Gene Symbol

TESK2

HGNC ID

HGNC:11732

ORF Size (aa)

1629

ORF Size (bp)

1629 bp

RefSeq ID

NM_007170

RefSeq Synonyms

NM_007170, NM_001320800, BC033085,

Species

human

UniGene ID

Hs.591499

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.