human TCTN2 shRNA silencing AAV

Name 
AAV-h-TCTN2-shRNA
Cat No 
shAAV-225258
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TCTN2.

shAAV-225258
AAV-h-TCTN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TCTN2 (tectonic family member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C12orf38; JBTS24; MKS8; TECT2
Description (Vector)
TCTN2 encodes a type I membrane protein that belongs to the tectonic family. Studies in mice suggest that this protein may be involved in hedgehog signaling, and essential for ciliogenesis. Mutations in this gene are associated with Meckel syndrome type 8. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
79867
Gene Name (Vector)
tectonic family member 2
Gene Symbol
TCTN2
HGNC ID
HGNC:25774
ORF Size (aa)
2094
ORF Size (bp)
2094 bp
RefSeq ID
NM_024809
RefSeq Synonyms
NM_024809, NM_001143850, BC009112,
Species
human
UniGene ID
Hs.167165

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.