human TCEB3B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ELOA2.
shAAV-225196
AAV-h-TCEB3B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ELOA2 (elongin A2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HsT832; TCEB3B; TCEB3L
Description (Vector)
TCEB3B encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.
Gene ID
51224
Gene Name (Vector)
elongin A2
Gene Symbol
ELOA2
HGNC ID
HGNC:30771
ORF Size (aa)
2262
ORF Size (bp)
2262 bp
RefSeq ID
NM_016427
RefSeq Synonyms
NM_016427, BC103911, BC036022,
Species
human
UniGene ID
Hs.375035
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.