human TBX20 shRNA silencing AAV

Name
AAV-h-TBX20-shRNA

Cat No
shAAV-225157

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human TBX20.

shAAV-225157

AAV-h-TBX20-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TBX20 (T-box 20). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ASD4

Description (Vector)

TBX20 encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. TBX20 is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID

57057

Gene Name (Vector)

T-box 20

Gene Symbol

TBX20

HGNC ID

HGNC:11598

ORF Size (aa)

894

RefSeq ID

NM_001166220

RefSeq Synonyms

NM_001166220, NM_001077653, BC120946,

Species

human

UniGene ID

Hs.404167

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.