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human TBR1 shRNA silencing AAV

Name 
AAV-h-TBR1-shRNA
Cat No 
shAAV-225145
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TBR1.

shAAV-225145
AAV-h-TBR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TBR1 (T-box, brain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TBR-1; TES-56
Description (Vector)
TBR1 is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
Gene ID
10716
Gene Name (Vector)
T-box, brain 1
Gene Symbol
TBR1
HGNC ID
HGNC:11590
ORF Size (aa)
2049
ORF Size (bp)
2049 bp
RefSeq ID
NM_006593
RefSeq Synonyms
NM_006593, BC113418, BC104844,
Species
human
UniGene ID
Hs.210862

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.