human TBL1X shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TBL1X.
shAAV-225130
AAV-h-TBL1X-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TBL1X (transducin beta like 1X-linked). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EBI; SMAP55; TBL1
Description (Vector)
TBL1X has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Gene ID
6907
Gene Name (Vector)
transducin beta like 1X-linked
Gene Symbol
TBL1X
HGNC ID
HGNC:11585
ORF Size (aa)
1581
ORF Size (bp)
1581 bp
RefSeq ID
NM_005647
RefSeq Synonyms
NM_005647, NM_001139468, NM_001139467, NM_001139466, BC052304, BC032708,
Species
human
UniGene ID
Hs.495656
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.