human TBC1D15 shRNA silencing AAV

Name 
AAV-h-TBC1D15-shRNA
Cat No 
shAAV-225072
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TBC1D15.

shAAV-225072
AAV-h-TBC1D15-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TBC1D15 (TBC1 domain family member 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GAP for RAB7; GTPase-activating protein RAB7; RAB7-GAP; TBC1 domain family member 15; Tre2/Bub2/Cdc16 domain family member 15; Tre-2-budding uninhibited by benzimidazole-cell division cycle 16 domain, domain family member 15
Description (eCommerce)
TBC1D15 is a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2/Bub2/Cdc16 domain. TBC1D15 interacts with Ras-like protein in brain 5A and may function as a regulator of intracellular trafficking [taken from NCBI Entrez Gene (Gene ID: 64786)].
Description (Vector)
TBC1D15 encodes a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2/Bub2/Cdc16 domain. The encoded protein interacts with Ras-like protein in brain 5A and may function as a regulator of intracellular trafficking. Alternate splicing results in multiple transcript variants.
Gene ID
64786
Gene Name (eCommerce)
TBC1 domain family member 15
Gene Name (Vector)
TBC1 domain family member 15
Gene Symbol
TBC1D15
HGNC ID
HGNC:25694
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2076
ORF Size (bp)
2076 bp
Protein Name (eCommerce)
TBC1 domain family member 15
RefSeq ID
NM_022771
RefSeq Synonyms
NM_022771, NM_001146214, NM_001146213, BC028352,
Research Areas
Mitochondrion,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
TBC1D15 is a member of the Ras-like proteins in brain-GTPase activating protein superfamily that share a conserved Tre-2/Bub2/Cdc16 domain. TBC1D15 interacts with Ras-like protein in brain 5A and may function as a regulator of intracellular trafficking [taken from NCBI Entrez Gene (Gene ID: 64786)].
UniGene ID
Hs.595154
UniProt ID (eCommerce)
Q8TC07

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.