human TAZ shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TAZ.
shAAV-225052
AAV-h-TAZ-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TAZ (tafazzin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; Taz1
Description (Vector)
TAZ encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
Gene ID
6901
Gene Name (Vector)
tafazzin
Gene Symbol
TAZ
HGNC ID
HGNC:11577
ORF Size (aa)
789
RefSeq ID
NM_000116
RefSeq Synonyms
NM_181313, NM_181312, NM_181311, NM_001303465, NM_000116, BC011515,
Species
human
UniGene ID
Hs.409911
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.