human TAGLN shRNA silencing AAV

Name 
AAV-h-TAGLN-shRNA
Cat No 
shAAV-224943
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TAGLN.

shAAV-224943
AAV-h-TAGLN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TAGLN (transgelin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SM22; SMCC; TAGLN1; WS3-10
Description (Vector)
TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
6876
Gene Name (Vector)
transgelin
Gene Symbol
TAGLN
HGNC ID
HGNC:11553
ORF Size (aa)
606
RefSeq ID
NM_003186
RefSeq Synonyms
NM_003186, NM_001001522, BC093050, BC092415, BC065829, BC004927,
Species
human
UniGene ID
Hs.410977

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.