human TAF11 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TAF11.
shAAV-224911
AAV-h-TAF11-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TAF11 (TATA-box binding protein associated factor 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MGC:15243; PRO2134; TAF2I; TAFII28
Description (Vector)
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
6882
Gene Name (Vector)
TATA-box binding protein associated factor 11
Gene Symbol
TAF11
HGNC ID
HGNC:11544
ORF Size (aa)
636
RefSeq ID
NM_005643
RefSeq Synonyms
NM_005643, NM_001270488, BC021972,
Species
human
UniGene ID
Hs.112444
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.