human TADA2L shRNA silencing AAV

Name
AAV-h-TADA2L-shRNA

Cat No
shAAV-224905

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human TADA2A.

shAAV-224905

AAV-h-TADA2L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TADA2A (transcriptional adaptor 2A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ADA2; ADA2A; hADA2; KL04P; TADA2L

Description (Vector)

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.

Gene ID

6871

Gene Name (Vector)

transcriptional adaptor 2A

Gene Symbol

TADA2A

HGNC ID

HGNC:11531

ORF Size (aa)

1332

ORF Size (bp)

1332 bp

RefSeq ID

NM_001488

RefSeq Synonyms

NM_133439, NM_001488, NM_001291918, NM_001166105, BC011753, BC001172,

Species

human

UniGene ID

Hs.500066

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.