human TAC3 shRNA silencing AAV

Name 
AAV-h-TAC3-shRNA
Cat No 
shAAV-224887
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TAC3.

shAAV-224887
AAV-h-TAC3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TAC3 (tachykinin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HH10; NKB; NKNB; PRO1155; ZNEUROK1
Description (Vector)
TAC3 encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants.
Gene ID
6866
Gene Name (Vector)
tachykinin 3
Gene Symbol
TAC3
HGNC ID
HGNC:11521
ORF Size (aa)
366
RefSeq ID
NM_013251
RefSeq Synonyms
NM_013251, NM_001178054, BC032145,
Species
human
UniGene ID
Hs.9730

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.