human SYT5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SYT5.
shAAV-224856
AAV-h-SYT5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SYT5 (synaptotagmin 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 (PubMed 7597049)).(supplied by OMIM, Feb 2011)
Gene ID
6861
Gene Name (Vector)
synaptotagmin 5
Gene Symbol
SYT5
HGNC ID
HGNC:11513
ORF Size (aa)
1161
ORF Size (bp)
1161 bp
RefSeq ID
NM_003180
RefSeq Synonyms
NM_003180, NM_001297774, BC046157,
Species
human
UniGene ID
Hs.631566
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.