human SULF2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SULF2.
shAAV-224703
AAV-h-SULF2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SULF2 (sulfatase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HSULF-2
Description (Vector)
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 (PubMed 16192265)).(supplied by OMIM, Mar 2008)
Gene ID
55959
Gene Name (Vector)
sulfatase 2
Gene Symbol
SULF2
HGNC ID
HGNC:20392
ORF Size (aa)
2613
ORF Size (bp)
2613 bp
RefSeq ID
NM_018837
RefSeq Synonyms
NM_198596, NM_018837, NM_001161841, BC110539, BC020962,
Species
human
UniGene ID
Hs.162016
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.