human STMN2 shRNA silencing AAV

Name
AAV-h-STMN2-shRNA

Cat No
shAAV-224609

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human STMN2.

shAAV-224609

AAV-h-STMN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human STMN2 (stathmin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SCG10; SCGN10

Description (Vector)

STMN2 encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

Gene ID

11075

Gene Name (Vector)

stathmin 2

Gene Symbol

STMN2

HGNC ID

HGNC:10577

ORF Size (aa)

540

RefSeq ID

NM_007029

RefSeq Synonyms

NM_007029, NM_001199214, BC006302,

Species

human

UniGene ID

Hs.521651

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.